Cerebral oedema with coning in diabetic keto-acidosis. Report of 2 survivors.

Fatal cerebral oedema in adult diabetic ketoacidosis.

In this report, a case of adult onset fatal cerebral oedema as a rare complication of diabetic ketoacidosis (DKA) is described and confirmed at post-mortem pathological examination. The pathogenesis of cerebral oedema due to DKA is still unknown. Potential mechanisms include the administration of sodium bicarbonate leading to intracellular acidosis, excessive fluid infusion causing swelling of ...

The risk and outcome of cerebral oedema developing during diabetic ketoacidosis.

BACKGROUND Cerebral oedema is a major cause of morbidity and mortality in children with insulin dependent diabetes. AIMS To determine the risk and outcome of cerebral oedema complicating diabetic ketoacidosis (DKA). METHODS All cases of cerebral oedema in England, Scotland, and Wales were reported through the British Paediatric Surveillance Unit between October 1995 and September 1998. All ...

News About the Treatment of Diabetes with Insulin

One of the most important advances in imsulin therapy has been the commercial production of highly purified single peak and single component insulin. The routine use of these pre9ara -tions have reduced insulin allergy and abolished insulin lipo­atrophy.  The subject of low dose insulin infusion in diabetic keto - acidosis in still controversial,but is based on sound theoreti - cal and experim...

Hyperglycaemia‐related complications at the time of diagnosis can cause permanent neurological disability in children with neonatal diabetes

BACKGROUND Children with neonatal diabetes often present with diabetic ketoacidosis and hence are at risk of cerebral oedema and subsequent long-term neurological deficits. These complications are difficult to identify because neurological features can also occur as a result of the specific genetic aetiology causing neonatal diabetes. CASE REPORTS We report two cases of neonatal diabetes wher...

Development of severe diabetic keto-acidosis with shock after changing interferon-beta into interferon-alpha for chronic hepatitis C.